I posted a similar thread when I moved up here in July '09 mate.
Best places I've found are either the Lass O'Gowrie (landlord is a poster on here) on Charles Street, just off Oxford Road behind the BBC; very friendly pub, loads of screens, reasonable prices and never any loutish behaviour. All footie fans seem to co-exist peacefully in there - definitely my #1 footballing haunt.
The other I occasionally frequent is Joshua Brooks next door, on the corner of Princess Street, opposite the Ibis - again, landlords are Yiddos and you get a decent crowd in there - I was there for Spurs vs Chelsea this season and nearly everyone there was a Yid. Again, none of the drunken louts in football shirts who you'd find in places like Deansgate/Quay Street Walkabout, or Yates on Portland Street.
General rule of thumb - avoid Deansgate for football. Although if you're in Fallowfield then I doubt you'd venture all that way anyway!
Good luck finding somewhere mate, give us a shout if you're going to watch any of the matches soon, I'm usually there.
There do seem to be a large amount of us around Manchester to be honest.
The two venues I listed seem to have the highest concentration of Spurs fans from the places I've been to but I know there are many others - I've just not been.
We ll have to have a meet up for one of the games
Joshua Brooks is a good shout!
Id definitely be up for a meet of the Manchester Spurs contingent sometime.